Methodology
The science behind every verdict.
How we collect, verify, and ship the interaction data that powers PharmaGuide — including who reviews it, what AI does and doesn't do, and where we draw the line.
01 · Why methodology matters
In a market full of opinions, we show our work.
- 01
Traceability
Every interaction warning is traceable to a regulatory source, peer-reviewed publication, or professional reference. No anonymous claims.
- 02
Accuracy
Content is verified against primary sources and reviewed by licensed clinicians before it ships. Updates are dated and visible.
- 03
Accountability
We say what we do — and what we don't. The boundaries are explicit. No marketing-speak hiding the limits.
02 · Where our data comes from
Four primary sources. No anonymous claims.
- FDA
FDA Resources
- Dietary Supplement Label Database (DSLD)
- Adverse Event Reporting System (FAERS)
- Warning letters and safety alerts
- Current Good Manufacturing Practice (cGMP) records
Product identification · safety alerts · manufacturing disclosures
- NIH
NIH Resources
- Office of Dietary Supplements (ODS)
- National Center for Complementary and Integrative Health (NCCIH)
- DailyMed (drug labeling)
- Dietary Supplement Ingredient Database
Ingredient information · efficacy research · safety profiles
- PUB
Clinical Literature
- PubMed / MEDLINE
- Cochrane Library systematic reviews
- Journal of Dietary Supplements
- Drug-nutrient interaction studies
Interaction mechanisms · clinical evidence · contraindications
- PRO
Professional Resources
- Natural Medicines Database
- Clinical pharmacology references
- Drug interaction databases
- Professional society guidelines
Cross-referencing interactions · clinical context
We do not access medical records, pharmacy systems, or any personal health data outside what you put into the app.
03 · Our 5-step process
From source to verdict, every interaction.
- 01
Source identification
We start from authoritative sources only — peer-reviewed, government-published, or recognized by professional clinical societies. No blog posts, no influencer claims, no unverified registries.
- 02
Data extraction and analysis
Information is structured into ingredient profiles with explicit citations. Each interaction is mapped to its mechanism, evidence level, and clinical context.
Output · Structured ingredient profiles with cited sources - 03
Pharmacist verification
A licensed clinical pharmacist reviews every interaction before it ships — checking the science, the framing, and the recommendation against current practice standards.
Reviewer · Dr. Pham L., PharmD - 04
Clinical advisory review
A second reviewer reads from the patient-education angle: is the language clear, the framing accessible, the safety context unambiguous?
Reviewer · Miriam D., NP - 05
Publication and ongoing monitoring
Once published, content goes into an ongoing review cycle. FDA alerts, new research, or regulatory changes trigger immediate updates.
Schedule · Quarterly systematic reviews + priority alerts as needed
04 · Medical advisory team
Real clinicians, named.
Dr. Pham L., PharmD
Clinical Pharmacist
PharmD · 15+ years clinical pharmacy
Focus · Drug-supplement interactions · pharmacovigilance · clinical accuracy review
Miriam D., NP
Nurse Practitioner
NP · integrative health practice
Focus · Patient education · integrative health · content accessibility
05 · AI transparency
AI does some of the work. Humans do the rest.
We use AI to scale the parts that benefit from scale. We use clinicians for everything else. Here's exactly where the line is.
What AI does
- Process and structure data from multiple sources
- Identify potential interactions documented in the literature
- Generate initial drafts of educational content
- Power the AI Guidance Chat for in-app questions
What AI does not do
- Generate original research or clinical recommendations
- Diagnose medical conditions or symptoms
- Recommend specific treatments or dosages
- Access personal health records or medical history
- Replace the judgment of a licensed healthcare professional
06 · Limitations and scope
Built to inform. Not to replace.
PharmaGuide is
- An educational information platform
- A tool to support informed conversations with your healthcare provider
- A resource for understanding documented interactions
- Reviewed by licensed healthcare professionals
PharmaGuide is not
- A medical device or diagnostic tool
- A replacement for professional medical advice
- A source of treatment recommendations
- A guarantee of supplement safety or efficacy
Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.
Want to see it in action?
The methodology is the foundation. The product is the proof.
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See it in practice and what we're writing about.
Features
The 6 pillars in depth
Medication depletion · Stack intelligence · Quality transparency · Personal fit · Nutrient accumulation · Recall awareness.
ReadBlog
Evidence-graded writing
Long-form guides on interactions, depletions, recalls — every claim cited, every post reviewed.
ReadFAQ
The questions we hear most
Privacy, accuracy, special populations, pricing, launch timing — answered honestly.
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